Toxoplasma gondii monoclonal antibodies T7

Description

Toxoplasma gondii is a parasitic intestinal coccidia, the only member of the Apicomplexa that primarily infects feline hosts but infects a variety of intermediate organisms.
Toxoplasma gondii causes asymptomatic or symptomatic reactions in people with severe immune reactions: fever, lymphadenopathy, etc. Congenital diseases lead to visual and mental disorders, and the disease is associated with problems of the central nervous system in immunocompromised patients. Vigilance is critical for pregnant women and those with weakened immunity, as Toxoplasma can very often cause damage to the fetus.
Typically, the diagnosis of toxoplasmosis is based on serological tests. Early infection is characterized by the production of IgM antibodies, which peak after 1-3 months, and some patients maintain high levels for many years, so the presence of these antibodies does not necessarily indicate primary toxoplasmosis. IgG antibodies appear after 2 weeks and reach a maximum after 3 months, remaining stable for 6 months and then gradually decreasing. Elevated IgG titers may indicate primary infection or reactivation. Enzyme immunoassay methods detect IgG avidity indicators, which makes it possible to differentiate a recent infection from a long-standing one. Immunogenic sites are located on the surface of the parasite or secreted in the host cells and are recognized by IgG and IgM antibodies. Typically, immunoassays use Toxoplasma gondii TLA lysate containing a mixture of native antigens.
The company offers mouse monoclonal antibodies to native T. gondii antigens. Some clones are characterized as high avidity and some as low avidity. Monoclonal antibodies to T. gondii have been validated in ELISA and can be used as synthetic positive controls in antibody avidity determinations or as calibrators for quantitative assays.

ADVANTAGES

• Toxoplasma gondii Mabs are obtained to the native antigen, therefore they can be used with raw materials from various manufacturers.
• All monoclonal antibodies can be provided as ready-made internal controls for use in indirect ELISA with peroxidase antispecies conjugates.
• We provide samples for testing free of charge.
• Our prices are very competitive, which will significantly reduce your production costs.

We recommend stabilizers for storing internal controls.